It occurs only in women and is strongly associated with problems related to blood sugar balance, such as insulin resistance and diabetes.
Insulin secretion increases the production and secretion of androgens from the adrenal gland, where they are made. Androgens are the ‘male’ hormones that both men and women have.
|(Left) Irving Freiler Stein (1887-1976); (right) Michael Leo Leventhal (1901-1971)|
The syndrome was first described in 1935 when American gynecologists Irving F. Stein, Sr., and Michael L. Leventhal associated the presence of ovarian cysts with anovulation.
The basic symptoms are the following:
*Irregular ovulation with or without a monthly period
*A relative lack of menstrual periods or irregular monthly periods
*Hyper hair growth on the face and body
*Thinning scalp hair
*Many unruptured follicles on the ovaries, misdiagnosed as cysts